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A Beginners' Guide to Molecular Biology



You are here: The Cell

The biology of the cell

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Table of contents

Organisation of the cell

Molecular content of the cell

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Organization of the cell

The whole picture

There is not one cell , but many different types of cells . Cells are like people. Look around you and you will see that everyone has their own job. Cells are the same. They all have their own job, and are therefore specialised. The theoretical ask Dr Chromo! plant cell used in these pages does not exist, it is just an example I created in order to show all the elements at once. Often, in a specialised cell, not all the elements are present, but some are numerous. We will see that when examining some examples of cells .


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The elements of a cell, sorted by function

Growth

At the cellular level, whichever element is involved in cell division, or the production of protein, takes part in the growth of the cell
The nucleus
The ribosomes ask Dr Chromo!
The endoplasmic ask Dr Chromo! reticulum ask Dr Chromo!
The Golgi apparatus
The vacuoles
The centrioles ask Dr Chromo!

Moving

Movements at the cellular level, are performed with the contribution of :
The centriole
The cytoskeleton ask Dr Chromo!
Actin ask Dr Chromo! and tubulin ask Dr Chromo! proteins
Flagella or undulipodia - external to the cell

Eating

Or incorporating nutrients, metabolising, producing energy, excreting involving:
The membrane
Some vacuoles
The mitochondrion ask Dr Chromo!
The chloroplast ask Dr Chromo! ,
only in plant cells
The cytoplasm : many enzymatic reactions take place there.

Multiplying

A cell does not, properly speaking, breed! The reproduction of some organisms contains a step when gametes are produced. This involves a cell division called meiosis . In an organism, the multiplication of cells is called mitosis .
The structures involved are:
The nucleus and its contents
The centriole
The membrane
The structures involved in growing
or production of matter


The elements (description)

Main Component Subcomponent Main Function
The Cell Membrane


plasma membrane
protection
cell interaction
permeability, endocytosis ask Dr Chromo! , and exocytosis ask Dr Chromo!
The Nucleus


chromatin ask Dr Chromo! and chromosomes
ask Dr Chromo! nucleolus ask Dr Chromo!
nucleoplasm ask Dr Chromo!
genetic information storage system
synthesis of ribosomes
The Cytoplasm


cytoskeleton
matrix, cytosol
ribosomes
cell mobility and shape
Glycolysis ask Dr Chromo!
Endomembrane System



nuclear envelope
endoplasmic reticulum
Golgi complex
nuclear permeability
synthesis and transport of material, protein synthesis, secretion.
Membrane organelles




mitochondria
chloroplasts
lysosomes ask Dr Chromo!
peroxisomes
cell respiration
photosynthesis
digestion
peroxidation (reaction involving H 2 O 2 oxidation )
Microtubule organelles

centriole and spindle
basal body, cilia, and flagella
cell division
cell motility


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Chemistry of the cell : the basics

    Water, salts, ions, and trace elements.

You need a bit of everything, and a lot of water...

    Nucleic acids

Macromolecules of the utmost importance: DNA is the major store of genetic information, and is transcribed ask Dr Chromo! into RNA . RNA is then translated ask Dr Chromo! into protein. This sequence of events is often referred as the central DOGMA ask Dr Chromo! of Molecular Biology and can be summarised in the form:

DNA -->(transcription)--> RNA--> (translation) --> Proteins

    Sugars...

Carbohydrates, the main source of cellular energy, and also structural components of cells.

    Lipids

Bipolar molecules whose configuration accounts for many of the biological membrane's properties. Some hormones (steroids ask Dr Chromo!) are derived from lipids

    Proteins ask Dr Chromo! ...

Built up from amino acids ask Dr Chromo! , they are the working parts of the whole. Enzymes, receptors, channels, pores, hormones, ....


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